The FDA-Approval of SPRAVATO® is a significant advancement in the treatment of depression—especially for individuals who have not found relief with traditional antidepressants. SPRAVATO® (esketamine) is a nasal spray that is designed for treatment-resistant depression and works differently from conventional medications—and offers rapid symptom relief for many patients.
At Prestige Clinic, we are proud to offer FDA-cleared SPRAVATO® as part of our comprehensive approach to mental wellness. Our team stays at the forefront of medical advancements to provide new hope to patients who have struggled for years. With personalized treatment plans and a focus on comfort and safety, we guide you through every step of the SPRAVATO® therapy process, helping you reclaim a better quality of life.
The FDA approval and clearance of SPRAVATO® (esketamine) is a milestone in mental health treatment, particularly for individuals living with treatment-resistant depression. Approved in 2019, SPRAVATO® is the first nasal spray medication of its kind, offering a fast-acting alternative for patients who have not responded to traditional oral antidepressants. Its approval came after multiple clinical trials demonstrated significant improvement in depressive symptoms when used alongside an oral antidepressant. Unlike conventional antidepressants, which may take weeks to become effective, SPRAVATO® can begin working within hours to days.
The FDA approval of SPRAVATO® was granted under a Risk Evaluation and Mitigation Strategy (REMS), ensuring its safe use under medical supervision. This safeguards patients while giving providers a powerful new tool to treat persistent, life-disrupting depression. With growing demand for faster, more effective treatment options, the FDA’s decision marks a turning point in how major depressive disorder (MDD) is addressed in clinical practice.
SPRAVATO® offers a unique approach to treating depression, setting it apart from traditional medications. After it was FDA-cleared, SPRAVATO® became a vital option for patients unresponsive to multiple antidepressant treatments. It is derived from ketamine, a medication with decades of safe use in anesthesia.
When administered as a nasal spray, it acts on the brain’s NMDA receptors to increase glutamate activity—believed to help reset mood-related neural pathways. Unlike selective serotonin reuptake inhibitors (SSRIs), which can take weeks to become effective, SPRAVATO® may reduce symptoms within a few treatments. At our clinic, this treatment is always given safely. Each session is supervised, ensuring patient safety and monitoring for side effects. You can trust that you are in excellent hands with our providers.
At Prestige Clinic, we are committed to offering the most effective and scientifically supported treatments available. FDA-cleared SPRAVATO® is a trusted, evidence-based option for those who have not found success with standard medications. It is also delivered in a convenient nasal spray that is very well-tolerated by our patients. We understand that depression is not one-size-fits-all, and we use a personalized approach to ensure each and every single one of our patients receives the care that best meets their needs.
Following FDA-approval and clearance of SPRAVATO®, countless patients have achieved relief from their treatment-resistant depression. Discover if you can be next. Book your consultation with our mental health providers today.